Inspired by our society’s continuous flows of changes, the research issue takes place in the context of nowadays cities represented as spaces designed without human dimension and highly monopolized by automobile usage. The topics of programmatic combination, social implication of the urban environment, architecture that is capable of responding to the needs of the society of the 21st century have been examined. The research emphasizes the relevance of neglecting the principles of typological design and introduces the concepts of mixed-use and hybrid architecture, models that are able to generate social interaction. As a result of the theoretical research, the project of architectural hybrid placed in the Italian city Latina has been proposed.