The paper studies the problem of drug detection using microfluidic chips. For the purpose of this thesis we have developed three types of microfluidic chips. Each chip is composed of 7 layers of PVC and 2 gold electrodes, and the different geometry of the microfluidic channel. After lamination, the first testing of chip was performed manually, and then using a syringe pump.When the liquid passes through a microfluidic channel, there is a change of the electrical parameters of the capacitor structure.This change is measured using impedance analyzer. Based on these results it is concluded that the using this method we can detect various concentrations of Tramadol (Trodon) in a solution such as an artificial saliva.