MICROFLUIDIC CHIP FOR DETECTION OF VARIOUS DRUGS
DOI:
https://doi.org/10.24867/08RB02CocicKeywords:
микрофлуидни чип;, ксурографија;, импедансна спектроскопија;, детекција лековаAbstract
Nowadays, counterfeit drugs are common problem and the bulk methods for drug analysis have a lot of limitations. In order to explore new techniques of drug testing and analysis, a microfluidic platform with silver electrodes was developed. It was made with a combination of three fabrication techniques and proved to be a good basis for further development of more complex microfluidic systems. The proposed microfluidic platform can be used to differentiate the right drugs, what is achieved by measuring electrical parameters such as the resistance or capacitance between the pairs of silver electrodes.
References
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[2] Fadi El-Jardali, Elie A Akl, Racha Fadlallah, Sandy Oliver, Nadine Saleh, Lamya El-Bawab, Rana Rizk, Aida Farha, Rasha Hamra, “Interventions to combat or prevent drug counterfeiting: a systematic review”, BMJ Open 2015
[3] https://www.who.int/news-room/fact-sheets/detail/substandard-and-falsified-medical-products
[4] Zhang M., Zhang J., Cheng T. C. E., Hua G., Xen Y., Liu Y., “The Effect of Unannounced Inspection on Prevention of Drug Discovery”, Vol. 28, No. 1, Systems Engineering Society of China, 2018
[5] https://www.fluigent.com/microfluidic-expertise/what-is-microfluidic/microfluidic-definitions-and-advantages/
[6] Damiati S., Kompella B. U., Damiati A. S., Kodzius R., „Microfluidic Devices for Drug Discovery Systems and Drug Screening”, Vol. 9, No. 103, Genes, 2018.
[7] Whitesides M. G., “The origins and the future of microfluidics”, Vol 442, Nature, 2006.
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Published
2020-08-09
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Section
Biomedical Engineering